BDBM50254111 (S)-3-(3,4-dichlorophenyl)-3-(1H-indol-4-yl)-N-methylpropan-1-amine hydrochloride::CHEMBL509403

SMILES CNCC[C@@H](c1ccc(Cl)c(Cl)c1)c1cccc2[nH]ccc12

InChI Key InChIKey=NKIBKNOODDQPIA-ZDUSSCGKSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254111   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50254111((S)-3-(3,4-dichlorophenyl)-3-(1H-indol-4-yl)-N-met...)
Affinity DataKi:  3.63nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-dawley rat frontal cortex by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50254111((S)-3-(3,4-dichlorophenyl)-3-(1H-indol-4-yl)-N-met...)
Affinity DataKi:  35.4nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50254111((S)-3-(3,4-dichlorophenyl)-3-(1H-indol-4-yl)-N-met...)
Affinity DataIC50:  14.9nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed