BDBM50254220 CHEMBL513339::N-{3-[(S)-2-[4-(2-Amino-ethyl)-piperidin-1-yl]-1-(3-carbamimidoyl-benzyl)-2-oxo-ethylsulfamoyl]-phenyl}-3-hydroxy-propionamide::US8569313, 68

SMILES NCCC1CCN(CC1)C(=O)[C@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1cccc(NC(=O)CCO)c1

InChI Key InChIKey=NFFDOZRPFRQRCW-QHCPKHFHSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50254220   

TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50254220(CHEMBL513339 | N-{3-[(S)-2-[4-(2-Amino-ethyl)-pipe...)
Affinity DataKi:  117nMAssay Description:Inhibition assay using matriptase enzymeMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM50254220(CHEMBL513339 | N-{3-[(S)-2-[4-(2-Amino-ethyl)-pipe...)
Affinity DataKi:  120nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254220(CHEMBL513339 | N-{3-[(S)-2-[4-(2-Amino-ethyl)-pipe...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254220(CHEMBL513339 | N-{3-[(S)-2-[4-(2-Amino-ethyl)-pipe...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254220(CHEMBL513339 | N-{3-[(S)-2-[4-(2-Amino-ethyl)-pipe...)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50254220(CHEMBL513339 | N-{3-[(S)-2-[4-(2-Amino-ethyl)-pipe...)
Affinity DataKi:  6.10E+4nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed