BDBM50254582 5-methyl-1-(2-((R)-3-methyl-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)phenyl)-N,N-diphenyl-1H-pyrazole-3-carboxamide::CHEMBL514298

SMILES C[C@@H]1Cc2ccccc2CN1C(=O)c1ccccc1-n1nc(cc1C)C(=O)N(c1ccccc1)c1ccccc1

InChI Key InChIKey=DJDZWMABYCHMDB-XMMPIXPASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254582   

TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254582(5-methyl-1-(2-((R)-3-methyl-1,2,3,4-tetrahydroisoq...)
Affinity DataIC50:  5.24E+3nMAssay Description:Inhibition of GST fused Bcl-xL (unknown origin) binding to biotinylated 16 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254582(5-methyl-1-(2-((R)-3-methyl-1,2,3,4-tetrahydroisoq...)
Affinity DataIC50:  110nMAssay Description:Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed