BDBM50254595 CHEMBL502066::N,N-dibutyl-5-methyl-1-(4-(2-(phenylthio)acetamido)-2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)phenyl)-1H-pyrazole-3-carboxamide

SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NC(=O)CSc2ccccc2)cc1C(=O)N1CCc2ccccc2C1

InChI Key InChIKey=YOALHDWNEMCDAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254595   

TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254595(CHEMBL502066 | N,N-dibutyl-5-methyl-1-(4-(2-(pheny...)
Affinity DataIC50:  400nMAssay Description:Inhibition of GST fused Bcl-xL (unknown origin) binding to biotinylated 26 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254595(CHEMBL502066 | N,N-dibutyl-5-methyl-1-(4-(2-(pheny...)
Affinity DataIC50:  600nMAssay Description:Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 26 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed