BDBM50254601 3-cyclopropyl-3-(dimethylamino)propyl dimethylcarbamate::CHEMBL480799

SMILES CN(C)C(CCOC(=O)N(C)C)C1CC1

InChI Key InChIKey=FFODSKAPRYZFQX-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254601   

TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254601(3-cyclopropyl-3-(dimethylamino)propyl dimethylcarb...)
Affinity DataKi:  3.98E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4 nAChR (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254601(3-cyclopropyl-3-(dimethylamino)propyl dimethylcarb...)
Affinity DataKi:  6.31E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254601(3-cyclopropyl-3-(dimethylamino)propyl dimethylcarb...)
Affinity DataKi:  4.00E+4nMAssay Description:Displacement of [3H]epibatidine from alpha3beta4 nAChR (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254601(3-cyclopropyl-3-(dimethylamino)propyl dimethylcarb...)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]MLA from alpha7 nAChR/5HT3A receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Copenhagen University

Curated by ChEMBL
LigandPNGBDBM50254601(3-cyclopropyl-3-(dimethylamino)propyl dimethylcarb...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at alpha3beta4 nAChR (unknown origin) expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed