BDBM50256888 (S)-benzyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(sulfamoylamino)hexan-2-ylcarbamate::CHEMBL473836

SMILES NS(=O)(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1nc(cs1)-c1ccccc1

InChI Key InChIKey=RKOLFARMYLKKLL-IBGZPJMESA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50256888   

TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50256888((S)-benzyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant C-terminal FLAG-tagged HDAC1 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50256888((S)-benzyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant N-terminal histidine-tagged HDAC6 expressed in baculovirus by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50256888((S)-benzyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant His-tagged HDAC6 expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50256888((S)-benzyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC1 expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50256888((S)-benzyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of HDAC1 in human 293T cells after 16 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed