BDBM50257018 (E)-methyl4-(2-((R,Z)-3-((4-chloro-2-(trifluoromethyl)phenylcarbamoyloxy)methyl)-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-1-yl)acetamido)but-2-enoate::4-{2-[3-(4-Chloro-2-trifluoromethyl-phenylcarbamoyloxymethyl) (3R)-2-oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl]-acetylamino}-but-2-enoic acid methyl ester::CHEMBL501901

SMILES COC(=O)\C=C\CNC(=O)CN1c2ccccc2C(=N[C@H](COC(=O)Nc2ccc(Cl)cc2C(F)(F)F)C1=O)c1ccccc1

InChI Key InChIKey=WFLUSHRKBAULOF-KGUVVTLUSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50257018   

TargetFalcipain 2(Plasmodium falciparum)
Universit£

Curated by ChEMBL
LigandPNGBDBM50257018((E)-methyl4-(2-((R,Z)-3-((4-chloro-2-(trifluoromet...)
Affinity DataKi:  17nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2 after 10 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Universit£

Curated by ChEMBL
LigandPNGBDBM50257018((E)-methyl4-(2-((R,Z)-3-((4-chloro-2-(trifluoromet...)
Affinity DataKi:  810nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50257018((E)-methyl4-(2-((R,Z)-3-((4-chloro-2-(trifluoromet...)
Affinity DataKi:  7.30E+3nMAssay Description:Inhibition of cathepsin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50257018((E)-methyl4-(2-((R,Z)-3-((4-chloro-2-(trifluoromet...)
Affinity DataKi:  7.30E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50257018((E)-methyl4-(2-((R,Z)-3-((4-chloro-2-(trifluoromet...)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of cathepsin L (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50257018((E)-methyl4-(2-((R,Z)-3-((4-chloro-2-(trifluoromet...)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed