BDBM50257547 CHEMBL4076286

SMILES FC(F)(F)c1c(ccn2c(CC3CC3)nnc12)-c1ccc(CNC2CCOCC2)c(Cl)c1

InChI Key InChIKey=SCOBFXVAWLTPQZ-UHFFFAOYSA-N

Data  1 KI  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257547   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257547(CHEMBL4076286)
Affinity DataKi:  62nMAssay Description:Binding affinity to human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257547(CHEMBL4076286)
Affinity DataEC50:  631nMAssay Description:Positive allosteric modulation of human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes assessed as increase in glutamate-induced...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257547(CHEMBL4076286)
Affinity DataKd:  54nMAssay Description:Binding affinity to human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed