BDBM50257596 CHEMBL4060306
SMILES Clc1cc(ccc1NC1CC1)-c1ccn2c(CC3CC3)nnc2c1Cl
InChI Key InChIKey=IIWHPWPVODSNOY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50257596
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
Affinity DataKd: 6.10nMAssay Description:Positive allosteric modulation of human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes assessed as increase in glutamate-induced...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair