BDBM50257823 CHEMBL4089551
SMILES Nc1nc(-c2ccc(cc2)S(N)(=O)=O)c2c(c[nH]c2n1)C#N
InChI Key InChIKey=MPTGZYHKBIOUAJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50257823
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde
Curated by ChEMBL
University of Strathclyde
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of IKKalpha in human U2OS cells assessed as decrease in FCS induced p100 phosphorylation at ser866/870 residues preincubated for 1 hr foll...More data for this Ligand-Target Pair