BDBM50259339 5-tert-butyl-8-(2-chlorophenyl)-9-(4-chlorophenyl)pyrido[3,2-e][1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one::CHEMBL466711

SMILES CC(C)(C)c1nc2nc(-c3ccccc3Cl)c(cc2c2n[nH]c(=O)n12)-c1ccc(Cl)cc1

InChI Key InChIKey=RCDDRZOJAVJMCL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259339   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259339(5-tert-butyl-8-(2-chlorophenyl)-9-(4-chlorophenyl)...)
Affinity DataIC50:  1.90nMAssay Description:Inverse agonist activity at human cannabinoid CB1R expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259339(5-tert-butyl-8-(2-chlorophenyl)-9-(4-chlorophenyl)...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259339(5-tert-butyl-8-(2-chlorophenyl)-9-(4-chlorophenyl)...)
Affinity DataIC50:  3.80E+3nMAssay Description:Binding affinity to human cannabinoid CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed