BDBM50259598 3-{[(1R)-1-Phenylethyl]amino}-4-(1H-pyrazol-3-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL524472

SMILES C[C@@H](Nc1c(Nc2ccn[nH]2)c(=O)c1=O)c1ccccc1

InChI Key InChIKey=MTSGTWVVCJFRLJ-SECBINFHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259598   

TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259598(3-{[(1R)-1-Phenylethyl]amino}-4-(1H-pyrazol-3-ylam...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259598(3-{[(1R)-1-Phenylethyl]amino}-4-(1H-pyrazol-3-ylam...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259598(3-{[(1R)-1-Phenylethyl]amino}-4-(1H-pyrazol-3-ylam...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed