BDBM50263099 CHEMBL4084466

SMILES Cc1cc(Nc2nc(Sc3ccc(NC(=O)C4CCCCC4)cc3)nc(n2)N2CCOCC2)n[nH]1

InChI Key InChIKey=QCZCDPXYRCMYOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263099   

TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263099(CHEMBL4084466)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 24 hrs followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263099(CHEMBL4084466)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed