BDBM50265349 4-(2'-methoxybiphenyl-4-yloxy)-2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridine::CHEMBL497791

SMILES COc1ccccc1-c1ccc(Oc2cncc3sc(cc23)-c2nnn[nH]2)cc1

InChI Key InChIKey=ATERWDADHHMHGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265349   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50265349(4-(2'-methoxybiphenyl-4-yloxy)-2-(2H-tetrazol-5-yl...)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of MEK1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50265349(4-(2'-methoxybiphenyl-4-yloxy)-2-(2H-tetrazol-5-yl...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant COT by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed