BDBM50265896 CHEMBL4070359

SMILES Cc1nn(-c2ccc(C)cn2)c2cc(ncc12)-c1ccc(cc1F)[C@H]1C[C@@H]1C(O)=O

InChI Key InChIKey=HTAFDYZRIYQJFP-SJORKVTESA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50265896   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50265896(CHEMBL4070359)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of Adenosine A2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50265896(CHEMBL4070359)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse GPR40 expressed in HEK293 cells assessed as increase in intracellular calcium level after 5 mins by FLUO-4-AM dye-based FLI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50265896(CHEMBL4070359)
Affinity DataEC50:  740nMAssay Description:Agonist activity at human GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50265896(CHEMBL4070359)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at mouse GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed