BDBM50266017 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-3H-1,2-dithiole-3-thione::CHEMBL462911

SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)-c1cc(=S)ss1

InChI Key InChIKey=XXWZFMCFBPXXFF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266017   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50266017(5-(3,5-di-tert-butyl-4-hydroxyphenyl)-3H-1,2-dithi...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as effect on prostaglandin E2 production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50266017(5-(3,5-di-tert-butyl-4-hydroxyphenyl)-3H-1,2-dithi...)
Affinity DataIC50:  3.64E+3nMAssay Description:Inhibition of human platelet COX1 assessed as effect on prostaglandin E2 production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed