BDBM50266186 1-methyl-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)naphthalen-1-yl)-1H-benzo[d]imidazol-2-amine::CHEMBL457984

SMILES CNc1nccc(n1)-c1cccnc1Oc1ccc(Nc2nc3ccccc3n2C)c2ccccc12

InChI Key InChIKey=FGQULRNTICLCRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266186   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50266186(1-methyl-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50:  250nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50266186(1-methyl-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)py...)
Affinity DataIC50:  240nMAssay Description:Inhibition of Tie2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed