BDBM50266958 CHEMBL4077940

SMILES CC(C)Oc1cc(ccc1N)C(=O)Nc1ccc(nc1OC(C)C)C(=O)Nc1ccc(cc1OC(C)C)C(O)=O

InChI Key InChIKey=CLABHIBFONXFKY-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50266958   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50266958(CHEMBL4077940)
Affinity DataKi:  179nMAssay Description:Inhibition of FITC-Ahx-GQVGRQLAIIGDDINR-CONH2 peptide binding to Bcl2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50266958(CHEMBL4077940)
Affinity DataKi:  1.79E+3nMAssay Description:Inhibition of FITC-Ahx-GQVGRQLAIIGDDINR-CONH2 peptide binding to MCl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50266958(CHEMBL4077940)
Affinity DataKi:  1.79E+3nMAssay Description:Binding affinity to Bak/Mcl-1 (unknown origin) protein protein interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50266958(CHEMBL4077940)
Affinity DataIC50:  394nMAssay Description:Inhibition of FITC-labeled Bak-BH3 peptide binding to Bcl-xL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50266958(CHEMBL4077940)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of Bak/Mcl-1 (unknown origin) protein protein interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50266958(CHEMBL4077940)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of FITC-labeled Bak-BH3 peptide binding to Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed