BDBM50267942 1-(4-(3,5-dichlorophenylsulfonyl)piperazin-1-yl)-2-phenylpropan-1-one::CHEMBL490024

SMILES CC(C(=O)N1CCN(CC1)S(=O)(=O)c1cc(Cl)cc(Cl)c1)c1ccccc1

InChI Key InChIKey=FPFNMMWHYYWULG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267942   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267942(1-(4-(3,5-dichlorophenylsulfonyl)piperazin-1-yl)-2...)
Affinity DataEC50:  0.300nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267942(1-(4-(3,5-dichlorophenylsulfonyl)piperazin-1-yl)-2...)
Affinity DataIC50:  220nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed