BDBM50268742 CHEMBL523752::N-(2-ethyl-6-methylbenzyl)-2,3-dimethylimidazo[1,2-a]pyridin-8-amine

SMILES CCc1cccc(C)c1CNc1cccn2c(C)c(C)nc12

InChI Key InChIKey=ABOWEPDTQXMFNL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50268742   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268742(CHEMBL523752 | N-(2-ethyl-6-methylbenzyl)-2,3-dime...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using diethoxyfluorescein as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268742(CHEMBL523752 | N-(2-ethyl-6-methylbenzyl)-2,3-dime...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268742(CHEMBL523752 | N-(2-ethyl-6-methylbenzyl)-2,3-dime...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268742(CHEMBL523752 | N-(2-ethyl-6-methylbenzyl)-2,3-dime...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using 7-benzyloxyquinoline as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268742(CHEMBL523752 | N-(2-ethyl-6-methylbenzyl)-2,3-dime...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268742(CHEMBL523752 | N-(2-ethyl-6-methylbenzyl)-2,3-dime...)
Affinity DataIC50:  500nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed