BDBM50269395 CHEMBL4101639
SMILES Nc1nc(Nc2ccc(cc2)N2CCN(CC2)C2CC3CCC2C3)nn1-c1nccc2ccccc12
InChI Key InChIKey=GHJCUXDFXLKDLW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50269395
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Rigel Pharmaceuticals
Curated by ChEMBL
Rigel Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal GST-tagged human Axl (464 to 885 end residues) cytoplasmic domain expressed in baculovirus expression system using HS1 pepti...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Rigel Pharmaceuticals
Curated by ChEMBL
Rigel Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 350nMAssay Description:Inhibition of Axl in human HeLa cells assessed as reduction in AKT phosphorylation at Ser 473 residues pre-incubated for 1 hr before preclustered ant...More data for this Ligand-Target Pair