BDBM50272276 CHEMBL499050::N-(6-Chloro-1,8-naphthyridin-3-yl)-3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanamide

SMILES Fc1ccc(-c2noc(CCC(=O)Nc3cnc4ncc(Cl)cc4c3)n2)c(Cl)c1

InChI Key InChIKey=GUXZMJXQQKUUOL-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272276   

TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272276(CHEMBL499050 | N-(6-Chloro-1,8-naphthyridin-3-yl)-...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272276(CHEMBL499050 | N-(6-Chloro-1,8-naphthyridin-3-yl)-...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272276(CHEMBL499050 | N-(6-Chloro-1,8-naphthyridin-3-yl)-...)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272276(CHEMBL499050 | N-(6-Chloro-1,8-naphthyridin-3-yl)-...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272276(CHEMBL499050 | N-(6-Chloro-1,8-naphthyridin-3-yl)-...)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272276(CHEMBL499050 | N-(6-Chloro-1,8-naphthyridin-3-yl)-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed