BDBM50274519 (2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3-hydroxymorphinan-6-yl]-3-(furan-3-yl)-N-methylprop-2-enamide::CHEMBL483566
SMILES CN([C@@H]1CC[C@H]2[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1
InChI Key InChIKey=PXGJPRXHBFMPLD-RGFCBMLDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50274519
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 8.82nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse cerebellumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0350nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair