BDBM50274519 (2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3-hydroxymorphinan-6-yl]-3-(furan-3-yl)-N-methylprop-2-enamide::CHEMBL483566

SMILES CN([C@@H]1CC[C@H]2[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1

InChI Key InChIKey=PXGJPRXHBFMPLD-RGFCBMLDSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274519   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50274519((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50274519((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50274519((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)
Affinity DataKi:  8.82nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50274519((2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3...)
Affinity DataIC50:  0.0350nMAssay Description:Agonist activity at kappa opioid receptor in ddy mouse vas deferens assessed as inhibition of electric stimulation-induced contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed