BDBM50275708 CHEMBL486737::N-(2-aminophenyl)-6-(7-(phenylsulfonyl)-2,7-diazaspiro[4.4]nonan-2-yl)nicotinamide

SMILES Nc1ccccc1NC(=O)c1ccc(nc1)N1CCC2(CCN(C2)S(=O)(=O)c2ccccc2)C1

InChI Key InChIKey=KPMJOTUARMGJAE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275708   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50275708(CHEMBL486737 | N-(2-aminophenyl)-6-(7-(phenylsulfo...)
Affinity DataKi:  2.85E+4nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50275708(CHEMBL486737 | N-(2-aminophenyl)-6-(7-(phenylsulfo...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human HDAC1 expressed in mammalian cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed