BDBM50275723 2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone::CHEMBL450553

SMILES CCN(CCCCCCn1c(=O)c2ccc3c4c(ccc(c24)c1=O)c(=O)n(CCCCCCN(CC)Cc1ccccc1OC)c3=O)Cc1ccccc1OC

InChI Key InChIKey=LMHQZKRKCUDJFH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50275723   

TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275723(2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo...)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275723(2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo...)
Affinity DataIC50:  9.69E+3nMAssay Description:Inhibition of self-induced amyloid beta (1-40) aggregation by thioflavin T formation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275723(2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo...)
Affinity DataIC50:  8.13E+3nMAssay Description:Inhibition of human recombinant AChE-induced amyloid beta (1-40) aggregation by thioflavin T formation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50275723(2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed