BDBM50276893 CHEMBL1193539

SMILES Oc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(sc2c1)-c1ccc(Cl)cc1

InChI Key InChIKey=CXNZLOIPQFMHLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276893   

TargetEstrogen receptor beta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50276893(CHEMBL1193539)
Affinity DataIC50:  1nMAssay Description:Antagonism of estrogen action in a mammary tumor cell line was assayed via inhibition of MCF-7 cell proliferation stimulated by 10 e-11 M 17-beta-est...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Jain University

Curated by ChEMBL
LigandPNGBDBM50276893(CHEMBL1193539)
Affinity DataIC50:  0.0460nMAssay Description:Displacement of [3H]17beta-estradiol from ER in human MCF7 cells after 18 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed