BDBM50278435 CHEMBL512665::N-butyl-N-(piperidin-4-yl)naphthalene-2-sulfonamide

SMILES CCCCN(C1CCNCC1)S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=BGQYUSCFJWWBHR-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50278435   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278435(CHEMBL512665 | N-butyl-N-(piperidin-4-yl)naphthale...)
Affinity DataKi:  716nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278435(CHEMBL512665 | N-butyl-N-(piperidin-4-yl)naphthale...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of radiolabeled dopamine reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278435(CHEMBL512665 | N-butyl-N-(piperidin-4-yl)naphthale...)
Affinity DataIC50:  14nMAssay Description:Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278435(CHEMBL512665 | N-butyl-N-(piperidin-4-yl)naphthale...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed