BDBM50279780 4''-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-ylsulfanyl)-3-trifluoromethyl-phenyl]-3,4,5,6-tetrahydro-2H-[1,2'']bipyridinyl-4-carboxylic acid::4''-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylsulfanyl)-3-trifluoromethyl-phenyl]-3,4,5,6-tetrahydro-2H-[1,2'']bipyridinyl-4-carboxylic acid::CHEMBL360918

SMILES OC(=O)C1CCN(CC1)c1cc(ccn1)-c1ccc(Sc2ccc3OCCOc3c2)c(c1)C(F)(F)F

InChI Key InChIKey=GRRUUHVYLVKVPJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279780   

TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50279780(4''-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-ylsulfanyl)...)
Affinity DataIC50:  71nMAssay Description:Inhibitory concentration against integrin LFA-1/ICAM-1 binding complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed