BDBM50283119 CHEMBL69604::{(1S,2R)-1-Benzyl-2-hydroxy-3-[(1R,2S)-1-((S)-2-hydroxy-indan-1-ylcarbamoyl)-2-phenyl-ethylamino]-propyl}-carbamic acid tert-butyl ester::{(1S,2R)-1-Benzyl-2-hydroxy-3-[(S)-1-((1S,2R)-2-hydroxy-indan-1-ylcarbamoyl)-2-phenyl-ethylamino]-propyl}-carbamic acid tert-butyl ester::{1-Benzyl-2-hydroxy-3-[1-(2-hydroxy-indan-1-ylcarbamoyl)-2-phenyl-ethylamino]-propyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12

InChI Key InChIKey=QHSSQFJZPOJIOL-NODASKEBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50283119   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283119(CHEMBL69604 | {(1S,2R)-1-Benzyl-2-hydroxy-3-[(1R,2...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human immunodeficiency virus type 1 (HIV-1) proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283119(CHEMBL69604 | {(1S,2R)-1-Benzyl-2-hydroxy-3-[(1R,2...)
Affinity DataIC50:  252nMAssay Description:Compound was evaluated in vitro for the inhibition of HIV protease, using a peptide hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283119(CHEMBL69604 | {(1S,2R)-1-Benzyl-2-hydroxy-3-[(1R,2...)
Affinity DataIC50:  229nMAssay Description:Inhibitory activity against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283119(CHEMBL69604 | {(1S,2R)-1-Benzyl-2-hydroxy-3-[(1R,2...)
Affinity DataIC50:  229nMAssay Description:Inhibition of HIV-1 protease was determined in vitroChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed