BDBM50284436 CHEMBL4174101

SMILES COc1ccc(CNC(=O)c2cccc(c2)C(C)Oc2ccnc(Nc3ncccn3)c2)cc1OC

InChI Key InChIKey=DCVDIUDYOUIQBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284436   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284436(CHEMBL4174101)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284436(CHEMBL4174101)
Affinity DataIC50:  440nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed