BDBM50284518 CHEMBL4168903

SMILES COc1cc(CNC(=O)c2cccc(c2)C(C)Oc2ccnc(Nc3cnn(C)c3)c2)cc(OC)c1OC

InChI Key InChIKey=GWRSHIJHFQGYOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284518   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284518(CHEMBL4168903)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284518(CHEMBL4168903)
Affinity DataIC50:  410nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed