BDBM50285422 (1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-ylsulfanyl]-pentyl}-1H-benzoimidazol-2-yl)-phenyl-amine::CHEMBL50528

SMILES COc1ccc(cc1)-c1nc(SCCCCCn2c(Nc3ccccc3)nc3ccccc23)[nH]c1-c1ccc(OC)cc1

InChI Key InChIKey=ZZVKYIORYKXMKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285422   

TargetSterol O-acyltransferase 1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285422((1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yl...)
Affinity DataIC50:  640nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285422((1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yl...)
Affinity DataIC50:  750nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes was measured by using AIV assayMore data for this Ligand-Target Pair
In DepthDetails Article