BDBM50287550 5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one::5-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-sulfonyl]-phenyl}-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one::CHEMBL53538

SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(CCO)CC1

InChI Key InChIKey=NEYKRKVLEWKOBI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287550   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287550(5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsul...)
Affinity DataIC50:  19nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287550(5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsul...)
Affinity DataIC50:  460nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287550(5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsul...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287550(5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsul...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed