BDBM50287946 1-[(2R,6S)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(4-nitro-benzenesulfonyl)-morpholin-2-yl]-4-chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]quinoline::CHEMBL64328

SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO[Si](C)(C)C(C)(C)C)O1)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=KJKHKONBZRHHSR-SQJMNOBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287946   

TargetGTPase HRas(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287946(1-[(2R,6S)-6-(tert-Butyl-dimethyl-silanyloxymethyl...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
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