BDBM50288405 CHEMBL95940::N-[(1-Dihydroxyboranyl-4-guanidino-butylcarbamoyl)-methyl]-N-methyl-3-phenyl-propionamide

SMILES CN(CC(=O)N[C@@H](CCCNC(N)=N)B(O)O)C(=O)CCc1ccccc1

InChI Key InChIKey=KZVJNASRNCDNTJ-AWEZNQCLSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50288405   

TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288405(CHEMBL95940 | N-[(1-Dihydroxyboranyl-4-guanidino-b...)
Affinity DataKi:  0.160nMAssay Description:In vitro for inhibition of thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288405(CHEMBL95940 | N-[(1-Dihydroxyboranyl-4-guanidino-b...)
Affinity DataKi:  0.610nMAssay Description:Compound was tested in vitro for inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTissue-type plasminogen activator(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288405(CHEMBL95940 | N-[(1-Dihydroxyboranyl-4-guanidino-b...)
Affinity DataKi:  51nMAssay Description:Compound was tested in vitro for inhibition of tissue plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50288405(CHEMBL95940 | N-[(1-Dihydroxyboranyl-4-guanidino-b...)
Affinity DataKi:  100nMAssay Description:Concentration necessary to double time for clot formation induced by bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288405(CHEMBL95940 | N-[(1-Dihydroxyboranyl-4-guanidino-b...)
Affinity DataKi:  460nMAssay Description:In vitro for inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails Article