BDBM50288413 CHEMBL101759::N-[(5-Amino-1-dihydroxyboranyl-pentylcarbamoyl)-methyl]-3,N-diphenyl-propionamide

SMILES NCCCC[C@H](NC(=O)CN(C(=O)CCc1ccccc1)c1ccccc1)B(O)O

InChI Key InChIKey=NZEDSGTYZINZBH-FQEVSTJZSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50288413   

TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288413(CHEMBL101759 | N-[(5-Amino-1-dihydroxyboranyl-pent...)
Affinity DataKi:  1.40nMAssay Description:In vitro for inhibition of thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50288413(CHEMBL101759 | N-[(5-Amino-1-dihydroxyboranyl-pent...)
Affinity DataKi:  150nMAssay Description:Concentration necessary to double time for clot formation induced by bovine thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288413(CHEMBL101759 | N-[(5-Amino-1-dihydroxyboranyl-pent...)
Affinity DataKi:  230nMAssay Description:In vitro for inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTissue-type plasminogen activator(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288413(CHEMBL101759 | N-[(5-Amino-1-dihydroxyboranyl-pent...)
Affinity DataKi:  280nMAssay Description:Compound was tested in vitro for inhibition of tissue plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails Article