BDBM50289945 3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid benzo[1,3]dioxol-5-yl ester::CHEMBL292802
SMILES Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccc3OCOc3c2)c1Br
InChI Key InChIKey=JQBUPYPWHBIMNX-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50289945
Affinity DataIC50: 5.74E+3nMAssay Description:In vitro binding affinity in a radioligand binding experiment by competition with [125I]-labeled endothelin-1 for ETB receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:In vitro binding affinity in a radioligand binding experiment by competition with [125I]-labeled endothelin-1 for ETA receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of I-ET-1 binding to human Endothelin A receptorMore data for this Ligand-Target Pair