BDBM50290838 4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline::CHEMBL98798
SMILES COc1cc2ncnc(Oc3cccc(Br)c3)c2cc1OC
InChI Key InChIKey=BRHOGFZRGDIAMT-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50290838
Affinity DataIC50: 70nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Lille
Curated by ChEMBL
University Of Lille
Curated by ChEMBL
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of recombinant human VEGFR-2-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human EGFR-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair