BDBM50291704 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2,2,2-trifluoro-ethyl ester::(R)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2,2,2-trifluoro-ethyl ester::CHEMBL347440
SMILES COc1ccc(cc1)[P@](=O)(OCC(F)(F)F)N1Cc2ccccc2C[C@@H]1C(=O)NO
InChI Key InChIKey=DZWVTHAIOWIVNT-ZQHDKMAOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50291704
Affinity DataKi: 3.70nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Inhibition of Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Inhibitory constant against recombinant human Matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Inhibition of Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Inhibitory constant against recombinant human stromelysin-1 (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
Affinity DataKi: 358nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
Affinity DataKi: 617nMAssay Description:Inhibitory constant against recombinant human gelatinase B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
Affinity DataIC50: 950nMAssay Description:In vitro amphiregulin shedding inhibitionMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Organon K.K.
Curated by ChEMBL
Organon K.K.
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of heparin-binding epidermal growth factor (HB-EGF) sheddingMore data for this Ligand-Target Pair