BDBM50292986 2-amino-4-(2-fluorophenyl)-5-oxo-7-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile::CHEMBL512573

SMILES Fc1ccccc1C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1

InChI Key InChIKey=HHAJJGVMNIFIKF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292986   

TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50292986(2-amino-4-(2-fluorophenyl)-5-oxo-7-phenyl-5,6,7,8-...)
Affinity DataIC50:  4.70E+3nMAssay Description:Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50292986(2-amino-4-(2-fluorophenyl)-5-oxo-7-phenyl-5,6,7,8-...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells by [3H]D-Asp uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50292986(2-amino-4-(2-fluorophenyl)-5-oxo-7-phenyl-5,6,7,8-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]D-Asp from human EAAT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50292986(2-amino-4-(2-fluorophenyl)-5-oxo-7-phenyl-5,6,7,8-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]D-Asp from human EAAT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed