BDBM50293166 CHEMBL495545::N-(4-(4-methylpiperazin-1-yl)phenyl)-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine
SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2cnn3ncccc23)cc1
InChI Key InChIKey=AUAUBVTWWCYNPP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50293166
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human CDK2 by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of GSK3beta by scintillation proximity assayMore data for this Ligand-Target Pair