BDBM50293554 CHEMBL553719::N,N-Dimethyl-4-(3-{3-[3-(2-phenoxy-phenyl)-ureido]-phenyl}-1H-pyrrolo[2,3-b]pyridin-5-yl)-benzenesulfonamide

SMILES CN(C)S(=O)(=O)c1ccc(cc1)-c1cnc2[nH]cc(-c3cccc(NC(=O)Nc4ccccc4Oc4ccccc4)c3)c2c1

InChI Key InChIKey=BEFIVNPNOGANIJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293554   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293554(CHEMBL553719 | N,N-Dimethyl-4-(3-{3-[3-(2-phenoxy-...)
Affinity DataIC50:  2.08E+4nMAssay Description:Inhibition of IGF1-induced human IGF1R phosphorylation expressed in mouse NIH-3T3 cells treated 2 hrs prior to IGF1 challenge by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed