BDBM50293855 4-{3-[(2R)-2,3-dihydroxypropyl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}-1-[(1S,3S,4R)-spiro[bicyclo[2.2.1]heptane-2,1'-cyclopropan]-3-ylmethyl]piperidine hydrochloride::CHEMBL564840
SMILES OC[C@H](O)Cn1c2ccccc2n(C2CCN(C[C@H]3[C@H]4CC[C@H](C4)C33CC3)CC2)c1=O
InChI Key InChIKey=DTAPURRKADLRKH-ZSXPUABSSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50293855
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]naltrindole from human cloned delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human ORL1 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as inhibition of acetophenacetin odeethylationMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C8 in human liver microsomes assessed as inhibition of paclitaxel 6-alpha-hydroxylationMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as inhibition of diclofenac 4'-hydroxylationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]U69593 from human cloned kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of testosterone 6-beta-hydroxylationMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Displacement of radiolabeled MK-499 from human ERG expressed in HEK293 cells coexpressing IKr channel proteinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]Tyr14-nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as inhibition of dextrometorphan O-demethylationMore data for this Ligand-Target Pair