BDBM50294121 CHEMBL550081::N-hydroxy-2-(N-isopropoxy-4'-(methylthio)biphenyl-4-ylsulfonamido)acetamide

SMILES CSc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N(CC(=O)NO)OC(C)C

InChI Key InChIKey=RPWGPXSVYLHGRZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50294121   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294121(CHEMBL550081 | N-hydroxy-2-(N-isopropoxy-4'-(methy...)
Affinity DataIC50:  77nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294121(CHEMBL550081 | N-hydroxy-2-(N-isopropoxy-4'-(methy...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294121(CHEMBL550081 | N-hydroxy-2-(N-isopropoxy-4'-(methy...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294121(CHEMBL550081 | N-hydroxy-2-(N-isopropoxy-4'-(methy...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294121(CHEMBL550081 | N-hydroxy-2-(N-isopropoxy-4'-(methy...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294121(CHEMBL550081 | N-hydroxy-2-(N-isopropoxy-4'-(methy...)
Affinity DataIC50:  37nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294121(CHEMBL550081 | N-hydroxy-2-(N-isopropoxy-4'-(methy...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed