BDBM50294122 CHEMBL560837::N-Hydroxy-2-(N-isopropoxy-4'-methoxybiphenyl-4-ylsulfonamido)acetamide

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N(CC(=O)NO)OC(C)C

InChI Key InChIKey=LBKCSOUMADYGHM-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50294122   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294122(CHEMBL560837 | N-Hydroxy-2-(N-isopropoxy-4'-methox...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294122(CHEMBL560837 | N-Hydroxy-2-(N-isopropoxy-4'-methox...)
Affinity DataIC50:  160nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294122(CHEMBL560837 | N-Hydroxy-2-(N-isopropoxy-4'-methox...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294122(CHEMBL560837 | N-Hydroxy-2-(N-isopropoxy-4'-methox...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294122(CHEMBL560837 | N-Hydroxy-2-(N-isopropoxy-4'-methox...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294122(CHEMBL560837 | N-Hydroxy-2-(N-isopropoxy-4'-methox...)
Affinity DataIC50:  65nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294122(CHEMBL560837 | N-Hydroxy-2-(N-isopropoxy-4'-methox...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294122(CHEMBL560837 | N-Hydroxy-2-(N-isopropoxy-4'-methox...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294122(CHEMBL560837 | N-Hydroxy-2-(N-isopropoxy-4'-methox...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed