BDBM50294124 2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-N-hydroxyacetamide::CHEMBL550350

SMILES CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccc(Cl)cc2)cc1

InChI Key InChIKey=DKTYDWAJILHINP-UHFFFAOYSA-N

Data  1 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50294124   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataKi:  25nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50:  19nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50:  19nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant MMP16More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50:  40nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294124(2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-y...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed