BDBM50295107 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid(3-pyrrolidin-1-yl-phenyl)-amide::CHEMBL559646

SMILES Nc1ccccc1-c1nnc(o1)C(=O)Nc1cccc(c1)N1CCCC1

InChI Key InChIKey=OIZAATYLDAIHIC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50295107   

TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50295107(5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic ...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain preincubated for 5 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50295107(5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic ...)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain preincubated for 5 mins before substrate addition in presence of 0.01% Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50295107(5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic ...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain preincubated for 5 mins before substrate addition in presence of 0.001% Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50295107(5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic ...)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain preincubated for 5 mins before substrate addition in presence of 0.001% bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed