BDBM50295108 5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid 2,5-dimethoxy-benzylamide::CHEMBL564453

SMILES COc1ccc(OC)c(CNC(=O)c2nnc(o2)-c2ccccc2N)c1

InChI Key InChIKey=ANWCCOIQPJIQLQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50295108   

TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50295108(5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic ...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain preincubated for 5 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50295108(5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic ...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain preincubated for 5 mins before substrate addition in presence of 0.01% Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50295108(5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic ...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain preincubated for 5 mins before substrate addition in presence of 0.001% Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50295108(5-(2-Amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic ...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain preincubated for 5 mins before substrate addition in presence of 0.001% bovine serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed