BDBM50297323 2-Ethyl-6-(spiro[chromene-2,4'-piperidine]-4-yl)-3,4-dihydroisoquinolin-1(2H)-one::CHEMBL551615
SMILES CCN1CCc2cc(ccc2C1=O)C1=CC2(CCNCC2)Oc2ccccc12
InChI Key InChIKey=SXIIMAFNJUWZKS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50297323
Affinity DataKi: 8.10nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence-based assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Adolor
Curated by ChEMBL
Adolor
Curated by ChEMBL
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells by voltage clamp assayMore data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair