BDBM50297455 1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-6-methylindolin-2-one::CHEMBL551140
SMILES Cc1ccc2C(N=O)C(=O)N(Cc3cc(F)cc4COCOc34)c2c1
InChI Key InChIKey=CEFHLBGJHWUOBZ-UHFFFAOYSA-N
Data 16 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50297455
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of p38alpha by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of AKT3More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of ERK2 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair